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Spot® Ex Endoscopic Tattoo

Spot Ex is for endoscopically tattooing lesions in the upper and lower GI Tract.

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The #1 Endoscopic Tattoo Choice of Gastroenterologists 

  • Spot Ex is the only tattoo a with dual indication for surgical localization and clinical surveillance1

Darker Tattoo Enables Fast and Easy Identification 2

  • Easier to find at future endoscopy or surgery because Spot Ex is a darker tattoo3
  • Tattooing has been shown to reduce OR time by up to 40 minutes4

Item Number:

  • GIS-46 (5 mL syringe)

For any questions or to receive a quote, please contact us.


Expedite Localization At Follow-up Procedures

  • By tattooing lesions with endoscopic tattoos, localization in colon resection surgery or post-polypectomy for follow-up colonoscopy can be fast and easy
  • Allows 100% visualization of the correct surgical site2
  • Decreases surgical procedure time and blood loss3

Frequently Asked Questions

Spot Ex comes in a prefilled, pre-assembled, Zero-Step Prep™ syringe with a roll proof cap. Spot Ex is sold in boxes of 10 syringes.

Spot Ex is the first and only endoscopic tattoo indicated for both surgical localization and clinical surveillance.

Clinical surveillance refers to a clinician’s choice to monitor, or follow-up with, a patient at future intervals based on practice guidelines. Endoscopic tattoos help ensure the providers identify the same area of interest at each surveillance interval.

Surgical localization refers to the surgeon’s need to precisely locate an area of interest that was previously identified endoscopically. Endoscopic tattoos placed by the referring gastroenterologist are readily located at the time of surgery, facilitating quicker surgical localization (1.)

Arteaga-Gonzalez 1 I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg . 2006. 30(4):605–611

0.5-0.75ml of Spot Ex should be injected submucosally into four quadrants distal to the lesion of interest. Use a 23 or 25 gauge injection needle at an angle so that the beveled tip of the needle is entirely beneath the mucosa. If the needle is inserted perpendicular to the mucosa, there is a risk of penetrating the serosa and injecting the marker directly into the peritoneal cavity.

Spot Ex come in boxes of 10 pre-filled syringes.

Spot Ex is indicated for 36 months

Store the product at room temperature. Store the syringe with the syringe tip pointed upward or lying on its side. Do not store with the syringe tip pointing down. Storing the syringe tip down may allow a portion of the carbon pigment to settle into the narrow syringe outlet and prevent it from being re-suspended.

Spot Ex reference

1. Spot Ex Instructions For Use. Rev 06. October 2019
2. Spot Ex Luminosity Lab Results. Northwestern Biological Imaging Facility. Nov 2017.
3. Lee. P., Finding Endoscopic Tattoos: The Impact of Contrast. GI Supply. 2018.
4. Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg. 2006. 30(4):605–611.

Spot reference

1. Data on file.
2. Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg. 2006. 30(4):605–611.

Spot Ex reference

1. Spot Ex Instructions For Use. Rev 06. October 2019
2. Spot Ex Luminosity Lab Results. Northwestern Biological Imaging Facility. Nov 2017.
3. Lee. P., Finding Endoscopic Tattoos: The Impact of Contrast. GI Supply. 2018.
4. Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg. 2006. 30(4):605–611.

Spot reference

1. Data on file.
2. Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg. 2006. 30(4):605–611.

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